GLP-1 Dosage Calculator

Verify if your current medication dose aligns with the standard clinical titration schedules for GLP-1 agonists.

Select the drug you are prescribed

Total weeks since your first injection

The mg dose you are currently taking

Dose Comparison = Current Dose vs. Clinical Titration Table (4-week intervals)
Example: Week 6 on Semaglutide at 0.25mg. Standard suggests 0.5mg by week 5. Status: Below Standard Titration.

How is the starting dose for GLP-1 medications determined?

Starting doses for GLP-1 agonists like Semaglutide (Ozempic/Wegovy) and Tirzepatide (Mounjaro/Zepbound) are standardized to minimize gastrointestinal side effects. For Semaglutide, the standard start is 0.25mg weekly. For Tirzepatide, it is 2.5mg weekly. These starting doses are not typically therapeutic; they serve as a "loading phase" to prime your receptors and reduce the likelihood of severe nausea or vomiting.

When should I increase my GLP-1 dosage?

Dosage increases typically occur every 4 weeks. The goal is to find the "Minimum Effective Dose"—the lowest dose that provides significant glycemic control or weight loss while maintaining an acceptable side-effect profile. If you are achieving your targets at a lower dose, many clinicians recommend staying there rather than escalating to the maximum dose.

What happens if I increase my dose too quickly?

Rapid escalation can lead to "GLP-1 crash," characterized by severe nausea, persistent vomiting, and potentially gastroparesis (stomach paralysis). Following the 4-week titration schedule allows the gut to adapt to the slowed gastric emptying. If severe side effects occur, doctors often suggest staying at the previous dose for an additional 4 weeks or even reducing the dose.

Do different GLP-1 drugs have the same dosage scales?

No. Semaglutide (Ozempic/Wegovy) and Tirzepatide (Mounjaro/Zepbound) have different molecular structures and potencies. Semaglutide is a GLP-1 only agonist, while Tirzepatide is a dual GLP-1 and GIP agonist. Consequently, their dosing scales differ (e.g., 2.4mg max for Wegovy vs 15mg max for Zepbound). Never compare milligram-for-milligram across different drug classes.